{"id":466,"title":"Doda decarboxylase leading to mortality","short_name":"Doda decarboxylase leading to mortality","created_at":"2022-08-28T20:47:04.000-04:00","updated_at":"2024-05-26T20:39:58.000-04:00","corresponding_author":{"id":18939,"created_at":"2024-05-26T20:39:48.000-04:00","updated_at":"2026-06-05T15:04:12.000-04:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":2051,"event":"Decrease, Tyrosine","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":2052,"event":"Decrease, dopa decarboxylase","event_type":"KeyEvent"},{"event_id":2053,"event":"Increase, Defects in tanning of new cuticle","event_type":"KeyEvent"},{"event_id":2054,"event":"Increase,  impairment of cuticle sclerotization","event_type":"KeyEvent"},{"event_id":2055,"event":"Increase,  pigmentation","event_type":"KeyEvent"},{"event_id":990,"event":"Increase, Incomplete ecdysis","event_type":"KeyEvent"},{"event_id":2056,"event":"Increase,  delay in oviposition","event_type":"KeyEvent"},{"event_id":350,"event":"Increase, Mortality","event_type":"KeyEvent"},{"event_id":2057,"event":"Decrease,  hatching of egg","event_type":"KeyEvent"}],"aop_aos":[],"relationships":[{"relation":3199,"upstream_event_id":2051,"upstream_event":"Decrease, Tyrosine","downstream_event_id":2052,"downstream_event":"Decrease, dopa decarboxylase"},{"relation":3200,"upstream_event_id":2052,"upstream_event":"Decrease, dopa decarboxylase","downstream_event_id":2053,"downstream_event":"Increase, Defects in tanning of new cuticle"},{"relation":3201,"upstream_event_id":2053,"upstream_event":"Increase, Defects in tanning of new cuticle","downstream_event_id":2054,"downstream_event":"Increase,  impairment of cuticle sclerotization"},{"relation":3202,"upstream_event_id":2053,"upstream_event":"Increase, Defects in tanning of new cuticle","downstream_event_id":2055,"downstream_event":"Increase,  pigmentation"},{"relation":3203,"upstream_event_id":2054,"upstream_event":"Increase,  impairment of cuticle sclerotization","downstream_event_id":990,"downstream_event":"Increase, Incomplete ecdysis"},{"relation":3204,"upstream_event_id":2055,"upstream_event":"Increase,  pigmentation","downstream_event_id":990,"downstream_event":"Increase, Incomplete ecdysis"},{"relation":3205,"upstream_event_id":990,"upstream_event":"Increase, Incomplete ecdysis","downstream_event_id":2056,"downstream_event":"Increase,  delay in oviposition"},{"relation":3206,"upstream_event_id":990,"upstream_event":"Increase, Incomplete ecdysis","downstream_event_id":350,"downstream_event":"Increase, Mortality"},{"relation":3207,"upstream_event_id":990,"upstream_event":"Increase, Incomplete ecdysis","downstream_event_id":2057,"downstream_event":"Decrease,  hatching of egg"}]}