{"id":501,"title":"Excessive iron accumulation leading to neurological disorders","short_name":"Excessive iron accumulation in Neuron, Neurological disorders","created_at":"2023-06-21T09:43:46.000-04:00","updated_at":"2024-05-26T20:39:59.000-04:00","corresponding_author":{"id":18938,"created_at":"2024-05-26T20:39:48.000-04:00","updated_at":"2024-05-26T20:39:48.000-04:00","subscribed":true,"novice":null},"aop_stressors":[],"aop_mies":[{"event_id":2149,"event":"Increased intracelluar Iron accumulation","event_type":"MolecularInitiatingEvent"}],"aop_kes":[{"event_id":1510,"event":"Oxidative Stress in Brain","event_type":"KeyEvent"},{"event_id":386,"event":"Decrease of neuronal network function","event_type":"KeyEvent"}],"aop_aos":[{"event_id":2150,"event":"Neurological disorder","event_type":"AdverseOutcome"}],"relationships":[{"relation":3503,"upstream_event_id":2149,"upstream_event":"Increased intracelluar Iron accumulation","downstream_event_id":1510,"downstream_event":"Oxidative Stress in Brain"},{"relation":3504,"upstream_event_id":1510,"upstream_event":"Oxidative Stress in Brain","downstream_event_id":386,"downstream_event":"Decrease of neuronal network function"},{"relation":3505,"upstream_event_id":386,"upstream_event":"Decrease of neuronal network function","downstream_event_id":2150,"downstream_event":"Neurological disorder"}]}