Developers' Handbooks

Ver. Release Date View Download Release Notes Forum Links
2.5 July 15, 2022 Digital Copy, v2.5 Download
  • Added section to define the AOP development strategy
  • Stressors replace with Prototypical Stressors
  • Guidance for Evidence Collection Strategy for Key Event Relationships
  • Guidance for describing modulating factors for Key Event Relationships and AOPs
  • Introduced tabular format for summarizing evidence supporting essentiality of Key Events
  • Guidance for discussing potential applications of AOPs
Pdf iconAOP_Developers_Handbook_2.5_release_notes.pdf
2.0 February 14, 2018 N/A N/A

OECD (2018), "Users' Handbook supplement to the Guidance Document for developing and assessing Adverse Outcome Pathways", OECD Series on Adverse Outcome Pathways, No. 1, OECD Publishing, Paris,

1.0 June 03, 2014 N/A N/A