Help and Guidance
The AOP-Wiki help pages provide descriptions of each field in the wiki and includes links to the relevant sections in the AOP Developers' Handbook for more information.
The online AOP Developers' Handbook contains all the information from the OECD AOP Developers' Handbook in a web accessible format. The original document is still available for download.
If you have any questions that are not addressed below please check the AOP Forum and/or Frequently Asked Questions page.
We have launched a training wiki to allow users to learn the new system before making changes on the new production wiki. You do not need to be an author on this wiki to be granted author status on the training wiki, but all information in the training wiki is purged periodically and no mechanism exists to migrate information from that system to this one. If you would like to request author privileges on the training wiki, please contact us at firstname.lastname@example.org.
A community of AOP developers and users is available to develop trainings for groups, projects, and institutions. If you are interested in exploring the possibility or setting up a training, please fill out this form and someone will respond to your request.
OECD AOP Webinars
The OECD has hosted a series of webinars focused on a variety of aspects related to Adverse Outcome Pathways. Topics include journal review of AOPs, training needs and opportunities, tips for AOP development, assembling and evaluating weight of evidence, and the AOP framework. The webinar recordings and slides can be found in the middle of this page.
Adverse Outcome Pathways: Development and evaluation of quantitative AOPs and examples of their application XVIth International Congress of Toxicology, Maastricht, Netherlands, September 18, 2022 More info here (CEC03)
Online Wiki Training
An Online course has been developed to promote knowledge of and participation in the AOP process, including submissions to the AOP Wiki. The course was designed and developed by etioLogic, LLC for the Human Toxicology Project Consortium, is now hosted on the "Animal-Free Safety Assessment (AFSA) Collaboration" website (AFSAcollaboration.org) and is freely available. The course can be downloaded as zip files from (Download) or run directly online by clicking on the links below.
For an overview and historical perspective of the AOP framework click here: https://aopwiki.org/training/aops/. For training on the AOP-Wiki: https://aopwiki.org/training/wiki/
For questions or suggestions regarding the course, please contact the course sponsor via the e-mail address available in the Read Me file at (Read Me).
Thanks to the Human Toxicology Project Consortium for sponsoring this new resource to support AOP development and to etioLogic for assembling this course.
Catalog of Training Materials and Resources
A variety of presentations, recordings, and other resources created by the AOP Community have been collected by the Animal Free Safety Assessment Collaboration. The collection can be explored here: https://www.afsacollaboration.org/tox21/get-trained/#training-resources.