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Increased, Estrogen receptor (ER) activity leads to Decreased, Progesterone from corpus luteum
Key Event Relationship Overview
AOPs Referencing Relationship
|AOP Name||Adjacency||Weight of Evidence||Quantitative Understanding||Point of Contact||Author Status||OECD Status|
|Increased dopaminergic activity leading to endometrial adenocarcinomas (in Wistar rat)||adjacent||Cataia Ives (send email)||Under Development: Contributions and Comments Welcome|
Life Stage Applicability
Key Event Relationship Description
This key event is commonly measured using the E2/P4 ratio.