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Increase, Regenerative cell proliferation (urothelial cells) leads to Increase, Hyperplasia (urothelial)
Key Event Relationship Overview
AOPs Referencing Relationship
|AOP Name||Adjacency||Weight of Evidence||Quantitative Understanding||Point of Contact||Author Status||OECD Status|
|Urinary bladder calculi leading to urothelial papillomas and carcinomas (in mouse and rat)||adjacent||Agnes Aggy (send email)||Under Development: Contributions and Comments Welcome|
|AOP for urothelial carcinogenesis due to chemical cytotoxicity by mitochondrial impairment||adjacent||Arthur Author (send email)||Under development: Not open for comment. Do not cite|