Stressor: 261
Title
Tetrabromobisphenol A
Stressor Overview
AOPs Including This Stressor
AOP Name | Evidence |
---|---|
Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity | Not Specified |
Chemical Table
Preferred name | DTXID | Casrn | jchem_inchi_key | indigo_inchi_key | User term |
---|---|---|---|---|---|
3,3',5,5'-Tetrabromobisphenol A | DTXSID1026081 | 79-94-7 | VEORPZCZECFIRK-UHFFFAOYSA-N | VEORPZCZECFIRK-UHFFFAOYSA-N | Tetrabromobisphenol A |
References
Fang, M., Webster, T. F., Ferguson, P. L. and Stapleton, H. M. (2015). Characterizing the peroxisome proliferator-activated receptor (PPARg) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. Environ. Health Perspect. 123, 166–172.
Riu, A., Grimaldi, M., le Maire, A., Bey, G., Phillips, K., Boulahtouf, A., Perdu, E., Zalko, D., Bourguet, W. and Balaguer, P. (2011). Peroxisome Proliferator-Activated Receptor [ gamma ] Is a Target for Halogenated Analogs of Bisphenol A. Perspect. Environ. Heal. Collect. Proquest Hosp. 119, 1227–1232.
Riu, A., Mccollum, C. W., Pinto, C. L., Grimaldi, M., Hillenweck, A., Perdu, E., Zalko, D., Bernard, L., Laudet, V., Balaguer, P., et al. (2014). Halogenated bisphenol-a analogs act as obesogens in zebrafish larvae (Danio rerio). Toxicol. Sci. 139, 48–58.
Suzuki, G., Tue, N. M., Malarvannan, G., Sudaryanto, A., Takahashi, S., Tanabe, S., Sakai, S. I., Brouwer, A., Uramaru, N., Kitamura, S., et al. (2013). Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. Environ. Sci. Technol. 47, 2898–2908.
ToxCastTM Data. “ToxCastTM Data.” US Environmental Protection Agency. http://www.epa.gov/ncct/toxcast/data.html.
Watt, J. and Schlezinger, J. J. (2015). Structurally-diverse, PPARγ-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells. Toxicology 331, 66–77.