>85 known Cyp2E1 substrates
AOPs Including This Stressor
|Cyp2E1 Activation Leading to Liver Cancer||High|
Events Including This Stressor
Low molecular weight compounds, including: molecular oxygen, acetone, acetaminophen, carbon tetrachloride, pyrazole, vinyl chloride, furan, chloroform, ethanol, benzene, acrylonitrile, trichloroethylene, aniline, N-nitrosodimethylamine, N-nitrosodiethylamine, diethylnitrosamine, thioacetamide, and toluene. A variety of substrates have been described (Lieber 1997, Tanaka, et al. 2000).