Stressor: 60
Title
Chemical name selected from established chemical ontologies or, depending on the information available, this could also refer to chemical categories (i.e., groups of chemicals with defined structural features known to trigger the MIE). It can also include non-chemical prototypical stressors such as genetic or environmental factors.
More help
Retinol
Stressor Overview
A structured data field that can be used to annotate an AOP with standardized terms identifying prototypical stressors known to trigger the MIE(s)/AOP.
More help
AOPs Including This Stressor
This table is automatically generated and lists the AOPs associated with this prototypical stressor.
More help
| AOP Name | Evidence |
|---|---|
| Protein Alkylation leading to Liver Fibrosis | High |
Chemical Table
A list of chemicals associated with a prototypical stressor.
More help
| Preferred name | DTXID | Casrn | jchem_inchi_key | indigo_inchi_key | User term |
|---|---|---|---|---|---|
| Retinol | DTXSID3023556 | 68-26-8 | FPIPGXGPPPQFEQ-OVSJKPMPSA-N | FPIPGXGPPPQFEQ-OVSJKPMPSA-N | Retinol |
References
List of the literature that was cited for this prototypical stressor.
More help
Takahashi and Breitman 1994 Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80.Arch Biochem Biophys;314(1):82-9.
Martin et al, 1986,Specific, covalent binding of an azidoretinoid to cellular retinoic acid-binding protein. Biochem Biophys Res Commun.26;135(1):124-30.