Stressor: 641
Title
Chemical name selected from established chemical ontologies or, depending on the information available, this could also refer to chemical categories (i.e., groups of chemicals with defined structural features known to trigger the MIE). It can also include non-chemical prototypical stressors such as genetic or environmental factors.
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Rosmarinic acid
Stressor Overview
A structured data field that can be used to annotate an AOP with standardized terms identifying prototypical stressors known to trigger the MIE(s)/AOP.
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AOPs Including This Stressor
This table is automatically generated and lists the AOPs associated with this prototypical stressor.
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AOP Name | Evidence |
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Inhibition of Fyna leading to increased mortality via decreased eye size (Microphthalmos) | Moderate |
Chemical Table
A list of chemicals associated with a prototypical stressor.
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References
List of the literature that was cited for this prototypical stressor.
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Jelić, D., Mildner, B., Koštrun, S., Nujić, K., Verbanac, D., Čulić, O., Antolović, R., & Brandt, W. (2007). Homology modeling of human Fyn kinase structure: Discovery of rosmarinic acid as a new Fyn kinase inhibitor and in Silico study of its possible binding modes. Journal of Medicinal Chemistry, 50(6), 1090–1100. https://doi.org/10.1021/jm0607202