AOPs Including This Stressor
Events Including This Stressor
|Dysregulation, ACE2 expression and activity|
The influenza virus is another biological stressor that appears to modulate ACE2 activity, but without binding to ACE2. Influenza infection also appears to up-regulate ACE2 mRNA in human nasal epithelia (Ziegler, 2020).
in epithelial kidney cells (Liu 2014, …..) and in mouse models of the disease where ACE2 modulation is associated with the severity of the virus induced disease ( Yang 2014, Zou 2014,…….).