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Aop: 268
AOP Title
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Uncoupling of oxidative phosphorylation leading to reproduction decline
Short name:
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Uncoupling of OXPHOS leading to reproduction decline
Graphical Representation
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Click to download graphical representation template
Authors
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You Songa
a Section for Environmental Toxicology, Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, NO-0349 Oslo, Norway
Contact: you.song@niva.no
Point of Contact
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Agnes Aggy
(email point of contact)
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Status
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| Author status |
OECD status |
OECD project |
SAAOP status |
| Under development: Not open for comment. Do not cite |
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Under Development |
This AOP was last modified on May 10, 2020 21:23
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Revision dates for related pages
| Page |
Revision Date/Time |
| Increase, Uncoupling of oxidative phosphorylation |
June 29, 2017 08:05 |
| Decrease, Mitochondrial ATP production |
September 16, 2017 10:14 |
| Decrease, Oogenesis |
April 30, 2020 16:41 |
| Decrease, Fecundity |
June 12, 2018 04:39 |
| Decrease, Ovulation |
September 16, 2017 10:15 |
| Increase, Uncoupling of OXPHOS leads to Decrease, Mitochondrial ATP production |
June 29, 2017 08:11 |
| Decrease, Mitochondrial ATP production leads to Decrease, Oogenesis |
June 29, 2017 08:11 |
| Decrease, Oogenesis leads to Decrease, Ovulation |
April 15, 2017 16:24 |
| Decrease, Ovulation leads to Decrease, Fecundity |
June 12, 2018 04:44 |
Abstract
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Background (optional)
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Summary of the AOP
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Events: Molecular Initiating Events (MIE)
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Key Events (KE)
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Adverse Outcomes (AO)
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(Including MIEs and AOs)
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Adjacency |
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Quantitative Understanding |
Network View
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Stressors
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Life Stage Applicability
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Taxonomic Applicability
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Sex Applicability
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Overall Assessment of the AOP
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Domain of Applicability
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Essentiality of the Key Events
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Evidence Assessment
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Quantitative Understanding
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Considerations for Potential Applications of the AOP (optional)
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References
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