API

Event: 1532

Key Event Title

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LSETAC-DNA mutation

Short name

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Increase in mutations

Biological Context

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Level of Biological Organization
Cellular

Cell term

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Organ term

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Key Event Components

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Process Object Action

Key Event Overview


AOPs Including This Key Event

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AOP Name Role of event in AOP
LSETAC DNA alkylation leading to infertility KeyEvent

Stressors

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Taxonomic Applicability

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Life Stages

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Sex Applicability

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Key Event Description

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replication over the alkyl adduct can cause insertion of an incorrect base in the DNA duplex (i.e., mutation)


How It Is Measured or Detected

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Next Gen Sequencing


Domain of Applicability

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References

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