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Increase, cell proliferation (hepatocytes) leads to Increase, Clonal Expansion of Altered Hepatic Foci
Key Event Relationship Overview
AOPs Referencing Relationship
|AOP Name||Adjacency||Weight of Evidence||Quantitative Understanding||Point of Contact||Author Status||OECD Status|
|PPARα activation leading to hepatocellular adenomas and carcinomas in rodents||adjacent||High||Moderate||Cataia Ives (send email)||Under development: Not open for comment. Do not cite||Under Development|