API XML

Aop: 291

AOP Title

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Train-Gui

Short name:

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HK training Gui

Graphical Representation

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Click to download graphical representation template

Authors

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Point of Contact

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Arthur Author   (email point of contact)

Contributors

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  • Arthur Author

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite


This AOP was last modified on June 10, 2019 04:18

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Revision dates for related pages

Page Revision Date/Time
Antagonism, Estrogen receptor September 16, 2017 10:14
Reduction, Vitellogenin synthesis in liver September 16, 2017 10:16
Reduction, Plasma vitellogenin concentrations September 16, 2017 10:14
Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development September 16, 2017 10:14
Reduction, Cumulative fecundity and spawning March 20, 2017 17:52
Decrease, Population trajectory September 26, 2017 11:33
Increased early life stages mortality June 10, 2019 04:07
Antagonism, Estrogen receptor leads to Early life stages mortality, increased June 10, 2019 04:18

Abstract

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Background (optional)

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Summary of the AOP

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Events: Molecular Initiating Events (MIE)

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Key Events (KE)

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Adverse Outcomes (AO)

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Sequence Type Event ID Title Short name
1 MIE 112 Antagonism, Estrogen receptor Antagonism, Estrogen receptor
3 KE 285 Reduction, Vitellogenin synthesis in liver Reduction, Vitellogenin synthesis in liver
4 KE 221 Reduction, Plasma vitellogenin concentrations Reduction, Plasma vitellogenin concentrations
5 KE 309 Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development Reduction, Vitellogenin accumulation into oocytes and oocyte growth/development
6 KE 78 Reduction, Cumulative fecundity and spawning Reduction, Cumulative fecundity and spawning
8 AO 360 Decrease, Population trajectory Decrease, Population trajectory
AO 1554 Increased early life stages mortality Early life stages mortality, increased

Relationships Between Two Key Events
(Including MIEs and AOs)

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Title Adjacency Evidence Quantitative Understanding
Antagonism, Estrogen receptor leads to Early life stages mortality, increased adjacent

Network View

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Stressors

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Life Stage Applicability

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Taxonomic Applicability

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Sex Applicability

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Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Evidence Assessment

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Quantitative Understanding

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Considerations for Potential Applications of the AOP (optional)

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References

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