| 2218 |
Binding of (ant)agonist to liver X receptor
Short Name
Binding of (ant)agonist to liver X receptor
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2219 |
Binding of (ant)agonist to peroxisome proliferator–activated receptor alpha
Short Name
Binding of (ant)agonist to PPAR alpha
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2220 |
Antagonism, Glucocorticoid hormone receptor
Short Name
GR antagonism
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2221 |
Altered Liver X receptor activity
Short Name
LXR activity, altered
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2222 |
Altered peroxisome proliferator–activated receptor alpha activity
Short Name
PPAR alpha activity, altered
|
0 |
Molecular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2223 |
Reduced number of oligodendrocytes
Short Name
Reduced number of oligodendrocytes
|
0 |
Cellular |
Apr 12, 2024 |
Apr 12, 2024 |
525: Reduced oligodendrocyte differentiation during neurodevelopment leading to impaired learning and memory
|
| 2224 |
Dysregulation of transcriptional expression within PPAR signaling network
Short Name
Dysregulation of transcriptional expression within PPAR signaling network
|
1 |
Molecular |
May 8, 2024 |
May 23, 2024 |
529: Perfluorooctanesulfonic acid (PFOS) binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism and subsequent liver steatosis
|
| 2225 |
Disrupted Lipid Storage
Short Name
Disrupted Lipid Storage
|
1 |
Cellular |
May 8, 2024 |
May 23, 2024 |
529: Perfluorooctanesulfonic acid (PFOS) binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism and subsequent liver steatosis
|
| 2226 |
Stressor binding PPAR isoforms
Short Name
Binding PPAR isoforms
|
1 |
Molecular |
May 8, 2024 |
May 22, 2024 |
529: Perfluorooctanesulfonic acid (PFOS) binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism and subsequent liver steatosis
|
| 2227 |
Disrupted PPAR isoform nuclear signaling
Short Name
Disrupted PPAR isoform nuclear signaling
|
1 |
Molecular |
May 14, 2024 |
May 22, 2024 |
529: Perfluorooctanesulfonic acid (PFOS) binding to peroxisome proliferator-activated receptors (PPARs) causes dysregulation of lipid metabolism and subsequent liver steatosis
|
| 2228 |
CYP450 Upregulation
Short Name
CYP450 Upregulation
|
0 |
Molecular |
Jun 3, 2024 |
Jun 20, 2024 |
532: CYP450 upregulation leads to Chronic kidney disease
|
| 2229 |
Acrolein accumulation
Short Name
Acrolein accumulation
|
0 |
Cellular |
Jun 3, 2024 |
Jun 18, 2024 |
532: CYP450 upregulation leads to Chronic kidney disease
|
| 2230 |
Increased, afferent artery vasoconstriction
Short Name
Increased, afferent artery vasoconstriction
|
1 |
Tissue |
Jun 6, 2024 |
Jun 21, 2024 |
534: Activation of Protein kinase C leads to Kidney Failure
|
| 2231 |
Increased, activation of renin, angiotensin, aldosterone system (RAAS)
Short Name
Increased, activation of RAAS
|
0 |
Cellular |
Jun 6, 2024 |
Jun 6, 2024 |
None
|
| 2232 |
Inhibition, COX-2 activity
Short Name
Inhibition, COX-2 activity
|
0 |
Molecular |
Jun 7, 2024 |
Jun 7, 2024 |
None
|
| 2233 |
Inhibition, NFAT
Short Name
Inhibition, NFAT
|
0 |
Molecular |
Jun 7, 2024 |
Jun 7, 2024 |
None
|
| 2234 |
Binding of C6R-Derived Protein K7
Short Name
Binding of C6R-Derived Protein K7
|
0 |
Molecular |
Jun 10, 2024 |
Jun 28, 2024 |
533: C6R-Derived Protein K7 following Monkeypox infection leads to heart failure
|
| 2235 |
Inhibition of E4 (Uracil-DNA Glycosylase)
Short Name
Inhibition of E4 (Uracil-DNA Glycosylase)
|
0 |
Molecular |
Jun 10, 2024 |
Jun 29, 2024 |
533: C6R-Derived Protein K7 following Monkeypox infection leads to heart failure
|
| 2236 |
Cardiac Heart Failure
Short Name
Cardiac Heart Failure
|
0 |
Organ |
Jun 10, 2024 |
Jun 29, 2024 |
533: C6R-Derived Protein K7 following Monkeypox infection leads to heart failure
|
| 2237 |
Increased, Endothelin protein
Short Name
Increased, Endothelin protein
|
0 |
Cellular |
Jun 19, 2024 |
Jun 20, 2024 |
534: Activation of Protein kinase C leads to Kidney Failure
|
| 2238 |
Disrupted calcium-dependent signalling pathway
Short Name
Disrupted calcium-dependent signalling pathway
|
0 |
Cellular |
Jun 19, 2024 |
Jun 19, 2024 |
None
|
| 2239 |
Increased, disregulation of smooth muscle cells
Short Name
Increased, disregulation of smooth muscle cells
|
0 |
Cellular |
Jun 19, 2024 |
Jun 19, 2024 |
None
|
| 2240 |
Activation, Protein Kinase C (PKC)
Short Name
Activation, Protein kinase C (PKC)
|
0 |
Molecular |
Jun 20, 2024 |
Jun 21, 2024 |
534: Activation of Protein kinase C leads to Kidney Failure
|
| 2241 |
Increased, AP-1 activity
Short Name
Increased, AP-1 activity
|
0 |
Cellular |
Jun 20, 2024 |
Jun 20, 2024 |
534: Activation of Protein kinase C leads to Kidney Failure
|
| 2242 |
Increased, edn1 gene expression
Short Name
Increased, edn1 gene expression
|
0 |
Cellular |
Jun 20, 2024 |
Jun 20, 2024 |
534: Activation of Protein kinase C leads to Kidney Failure
|