Key Event Relationships (KERs)

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Showing 1351 to 1375 of 2767 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
2101 1619: Increase, DNMT inhibition 1773: Decrease, Global DNA methylation Apr 30, 2020 Apr 30, 2020
3098 1619: Increase, DNMT inhibition 1461: Increase, DSB Nov 16, 2023 Nov 16, 2023
1911 1635: Increase, DNA strand breaks 155: Inadequate DNA repair May 19, 2019 Mar 8, 2024
1931 1635: Increase, DNA strand breaks 185: Increase, Mutations Jun 2, 2019 Jan 9, 2023
1939 1635: Increase, DNA strand breaks 1636: Increase, Chromosomal aberrations Jun 3, 2019 Jan 9, 2023
2074 1635: Increase, DNA strand breaks 1365: Increase, Apoptosis Apr 6, 2020 Apr 6, 2020
2587 1635: Increase, DNA strand breaks 1444: Increase, Follicular atresia Mar 1, 2022 Mar 1, 2022
2589 1635: Increase, DNA strand breaks 1775: Increase, Oocyte apoptosis Mar 1, 2022 Mar 1, 2022
2841 1635: Increase, DNA strand breaks 2098: Abnormal Neural Remodeling Jan 25, 2023 Mar 21, 2023
2856 1635: Increase, DNA strand breaks 2066: Altered Signaling Mar 10, 2023 Mar 21, 2023
732 746: Increase, Dopaminergic activity 747: Decreased, Prolactin Nov 29, 2016 Dec 3, 2016
770 746: Increase, Dopaminergic activity 773: Increase, Endometrial adenocarcinomas Nov 29, 2016 Dec 3, 2016 None
116 103: Increase, EcR agonism 60: Induction, Chitin degradation and resorption Nov 29, 2016 Dec 3, 2016 None
998 103: Increase, EcR agonism 988: Decrease, Circulating ETH Nov 29, 2016 Dec 3, 2016 None
999 103: Increase, EcR agonism 989: Decreased, synthesis and secretion of molting fluid proteases Nov 29, 2016 Dec 3, 2016 None
1007 103: Increase, EcR agonism 994: Decreased, Synthesis of molting fluid proteases Nov 29, 2016 Dec 3, 2016 None
1343 103: Increase, EcR agonism 1264: Increase, E75b expression Feb 9, 2017 Feb 9, 2017
2778 2068: Increase, Endothelial Dysfunction 2003: Vascular remodeling Sep 28, 2022 Sep 28, 2022 None
2784 2068: Increase, Endothelial Dysfunction 2069: Occurrence, Vascular Remodeling Oct 17, 2022 Mar 21, 2023
567 573: Increase, Energetic demands and therefore metabolic stress 574: Increased, Appetite and hunger Nov 29, 2016 Dec 3, 2016
2330 1860: Excitation of intracellular water 1632: Increase in RONS Apr 11, 2021 Apr 11, 2021 None
132 115: Increase, FA Influx 291: Accumulation, Triglyceride Nov 29, 2016 Mar 29, 2024
1417 1312: Increase, Fatty acid β-oxidation 1313: Decrease, cytosolic fatty acid Apr 13, 2017 Apr 13, 2017 None
1597 1444: Increase, Follicular atresia 1366: Decrease, Oogenesis Jun 29, 2017 Jun 29, 2017
2211 1444: Increase, Follicular atresia 328: Decrease, Fecundity Nov 25, 2020 Nov 25, 2020 None