AOPs

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Showing 51 to 75 of 476 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
66 Modulation of Adult Leydig Cell Function Subsequent Glucocorticoid Activation in the Fetal Testis Cataia Ives BY-SA 505: Decreased sperm quantity / quality in the adult, Decreased fertility 1.29
67 Modulation of Adult Leydig Cell Function Subsequent to Estradiaol Activation in the Fetal Testis Brendan Ferreri-Hanberry BY-SA 505: Decreased sperm quantity / quality in the adult, Decreased fertility 1.29
68 Modulation of Adult Leydig Cell Function Subsequent to Alterations in the Fetal Testis Protome Arthur Author BY-SA 661: Decreased testosterone by the fetal Leydig cells, Alterations in the fetal testis proteome 505: Decreased sperm quantity / quality in the adult, Decreased fertility 1.29
69 Modulation of Adult Leydig Cell Function Subsequent to Decreased Cholesterol Synthesis or Transport in the Adult Leydig Cell Agnes Aggy BY-SA 646: Decreased Cholesterol, Decreased sperm quantity and/or quality in the adult testis 1.29
70 Modulation of Adult Leydig Cell Function Subsequent to Proteomic Alterations in the Adult Leydig Cell Allie Always BY-SA 640: Decreased steroidogenesis, Proteomic alterations in the adult Leydig cell 520: Decreased sperm quantity or quality in the adult, Decreased fertility 1.29
71 Modulation of Adult Leydig Cell Function Subsequent to Glucocorticoid Activation Evgeniia Kazymova BY-SA 650: Stimulation of adult Leydig cells via the Adrenal Corticosterone, Increased Glucocorticoid 520: Decreased sperm quantity or quality in the adult, Decreased fertility 1.29
72 Epigenetic modification of PPARG leading to adipogenesis Cataia Ives BY-SA 1447: obesity 1.29
73 Xenobiotic Inhibition of Dopamine-beta-Hydroxylase and subsequent reduced fecundity Brendan Ferreri-Hanberry BY-SA 526: Inhibition, Inhibition of Dopamine-beta-hydroxylase 527: Decreased, Decreased fecundity 1.29
74 Modulation of Adult Leydig Cell Function Subsequent to Hypermethylation in the Fetal Testis Arthur Author BY-SA 662: Decreased testosterone by the fetal Leydig cells, Hypermethylation in the fetal testis 543: Decreased fertility in the adult, Decreased sperm quantity and/or quality in the adult testis 1.29
77 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 Agnes Aggy BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony 1.29
78 Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 Allie Always BY-SA 559: Activation, Nicotinic acetylcholine receptor 1.29
79 Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure Evgeniia Kazymova BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony 1.29
80 Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure Cataia Ives BY-SA 559: Activation, Nicotinic acetylcholine receptor 1.29
81 Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure Brendan Ferreri-Hanberry BY-SA None 1.29
82 Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure Arthur Author BY-SA None 1.29
84 Suppression of immune system contributes to impaired development and leads to colony loss/failure Agnes Aggy BY-SA None 1.29
85 Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure Allie Always BY-SA None 1.29
86 Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure Evgeniia Kazymova BY-SA None 1.29
87 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure Cataia Ives BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony 1.29
88 Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste Brendan Ferreri-Hanberry BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony 1.29
89 Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure Arthur Author BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony 1.29
90 Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2 Agnes Aggy BY-SA 559: Activation, Nicotinic acetylcholine receptor 1.29
91 Sodium channel inhibition leading to reduced survival Allie Always BY-SA 584: Inhibition, sodium channel 1.29
93 sodium channel inhibition leading to increased predation Evgeniia Kazymova BY-SA 584: Inhibition, sodium channel 588: Increased, predation 1.29
94 Sodium channel inhibition leading to congenital malformations Cataia Ives BY-SA 584: Inhibition, sodium channel 591: Increased, amputations 1.29