| 3213 |
1690: Decrease, testosterone levels |
219: Reduction, Plasma 17beta-estradiol concentrations |
May 8, 2024 |
May 8, 2024 |
1 AOP
|
| 3214 |
1690: Decrease, testosterone levels |
2139: Reduction, the ratio of E2/11-KT in plasma |
May 8, 2024 |
May 8, 2024 |
1 AOP
|
| 3225 |
1690: Decrease, testosterone levels |
520: Decreased sperm quantity or quality in the adult, Decreased fertility |
May 24, 2024 |
May 24, 2024 |
1 AOP
|
| 3227 |
1690: Decrease, testosterone levels |
791: Increased, Leutinizing hormone (LH) |
May 24, 2024 |
May 24, 2024 |
1 AOP
|
| 1934 |
1612: Decrease, testosterone level |
1613: Decrease, DHT level |
Jun 3, 2019 |
Jun 3, 2019 |
None
|
| 1936 |
1612: Decrease, testosterone level |
1614: Decrease, AR activation |
Jun 3, 2019 |
Jun 3, 2019 |
None
|
| 2129 |
1687: decrease, transcription of genes by AR |
1688: AGD, decreased |
May 11, 2020 |
May 11, 2020 |
1 AOP
|
| 1888 |
1622: Decrease, Transgenerational DNA methylation |
1621: Increase, Gene expression |
Apr 22, 2019 |
Apr 22, 2019 |
None
|
| 399 |
289: Decrease, Translocator protein (TSPO) |
413: Reduction, Testosterone synthesis in Leydig cells |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 437 |
289: Decrease, Translocator protein (TSPO) |
447: Reduction, Cholesterol transport in mitochondria |
Nov 29, 2016 |
Dec 2, 2016 |
1 AOP
|
| 2744 |
2051: Decrease, Tyrosine |
2052: Decrease, dopa decarboxylase |
Aug 28, 2022 |
Aug 28, 2022 |
1 AOP
|
| 1618 |
1452: decreased DNA methylation of tyrosine hydroxylase |
1447: obesity |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1620 |
1452: decreased DNA methylation of tyrosine hydroxylase |
1450: decreased dopamine |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1614 |
1450: decreased dopamine |
1451: decreased reward |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 2700 |
2026: decrease folate |
1561: Neural tube defects |
Jul 19, 2022 |
Jul 19, 2022 |
1 AOP
|
| 1814 |
1571: Decreased IL-1 production |
1572: Impaired IL-1 signaling |
Dec 25, 2018 |
Jun 25, 2019 |
None
|
| 1824 |
1571: Decreased IL-1 production |
1573: Suppressed MyD88 |
Jan 6, 2019 |
Jan 6, 2019 |
None
|
| 1619 |
1453: decreased methylation of dopamine transporter promoter |
1447: obesity |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1621 |
1453: decreased methylation of dopamine transporter promoter |
1450: decreased dopamine |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1811 |
1562: Decreased Na/K ATPase activity |
1563: Decreased proximal tubular vectorial transport |
Dec 20, 2018 |
Dec 20, 2018 |
1 AOP
|
| 2787 |
1562: Decreased Na/K ATPase activity |
1527: Increase, Cell membrane depolarization |
Oct 19, 2022 |
Oct 19, 2022 |
1 AOP
|
| 2293 |
1837: decreased oocyte maturation |
406: impaired, Fertility |
Mar 26, 2021 |
Mar 26, 2021 |
1 AOP
|
| 2278 |
1836: Decreased plasma Cortisol level |
1837: decreased oocyte maturation |
Feb 9, 2021 |
Feb 9, 2021 |
1 AOP
|
| 1917 |
1642: plasma retionic acid |
1640: Altered, Photoreceptor patterning |
May 22, 2019 |
May 22, 2019 |
1 AOP
|
| 3111 |
2203: Decreased proliferation of cortical NPCs |
2204: Altered brain morphology |
Jan 14, 2024 |
Jan 14, 2024 |
1 AOP
|