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Showing 1501 to 1525 of 2767 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
1241 1173: Increase, Peroxisomal Fatty Acid Beta Oxidation of Fatty Acids 209: Peptide Oxidation Nov 29, 2016 Dec 3, 2016 None
1230 1170: Increase, Phenotypic enzyme activity 716: Increase, cell proliferation (hepatocytes) Nov 29, 2016 Dec 31, 2020
1231 1170: Increase, Phenotypic enzyme activity 1171: Increase, Clonal Expansion of Altered Hepatic Foci Nov 29, 2016 Dec 3, 2016 None
2409 1892: increase, placental insufficiency 1893: increase, Preeclampsia May 31, 2021 May 31, 2021
254 220: Increase, Plasma vitellogenin concentrations 252: Increase, Renal pathology due to VTG deposition Nov 29, 2016 Nov 29, 2016
1474 1375: Increase, platelet aggregation 1367: Inhibit, gastric ulcer formation Apr 17, 2017 Apr 17, 2017
2555 1965: Increase, Pollen abnormal 1863: Decrease, Reproduction Jan 21, 2022 Jan 21, 2022
2634 623: Increase, predation 360: Decrease, Population growth rate Apr 6, 2022 Apr 6, 2022
1744 1524: Increase, Premature molting 350: Increase, Mortality May 24, 2018 Feb 17, 2021
774 774: Increase, Preneoplastic foci (hepatocytes) 719: Increase, hepatocellular adenomas and carcinomas Nov 29, 2016 Feb 15, 2017
2835 2097: Increase, Pro-Inflammatory Mediators 2098: Abnormal Neural Remodeling Jan 25, 2023 Feb 16, 2024
2839 2097: Increase, Pro-Inflammatory Mediators 341: Impairment, Learning and memory Jan 25, 2023 Mar 21, 2023
2339 1864: Increase, Programmed cell death 1479: Decrease, Leaf development Apr 11, 2021 Apr 11, 2021 None
2553 1864: Increase, Programmed cell death 1863: Decrease, Reproduction Jan 21, 2022 Jan 21, 2022
944 923: Increased goblet cell proliferation 921: Goblet cell hyperplasia Nov 29, 2016 Aug 27, 2021 None
2090 1767: Increase, Protein oxidation 1768: Increase, Abnormal osmoregulation Apr 30, 2020 Apr 30, 2020
2223 1767: Increase, Protein oxidation 1825: Increase, Cell death Dec 4, 2020 Dec 4, 2020 None
2802 2077: behavioral change leading to possible reduced feeding opportunity 1521: Decrease, Growth Nov 16, 2022 Nov 16, 2022
272 246: Increase, RBC congestion in liver 173: N/A, Methemoglobinemia, decreased hemoglobin, hematocrit, red blood cell number Nov 29, 2016 Dec 3, 2016
1466 1364: Increase, ROS 209: Peptide Oxidation Apr 15, 2017 Apr 15, 2017 None
1595 1364: Increase, ROS 1194: Increase, DNA Damage Jun 29, 2017 Jun 29, 2017 None
1598 1364: Increase, ROS 1445: Increased, LPO Jun 29, 2017 Jun 29, 2017 None
1876 1364: Increase, ROS 1608: Increase,Oxidative DNA damage Mar 19, 2019 Mar 19, 2019
2342 1364: Increase, ROS 1861: D1 protein deactivation Apr 11, 2021 Apr 11, 2021 None
2345 1364: Increase, ROS 1770: Decrease, MMP Apr 11, 2021 Apr 11, 2021 None