Prototypical Stressors

Showing 451 to 475 of 777 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

40	Methylmercuric(II) chloride	Methylmercuric(II) chloride, CAS-RN: 115-09-3, DTXSID5020813	17: Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory
218	metofluthrin	Metofluthrin, CAS-RN: 240494-70-6, DTXSID4034738	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
574	Metyrapone	Metyrapone, CAS-RN: 54-36-4, DTXSID1023314	349: Inhibition of 11β-hydroxylase leading to decresed population trajectory
289	Miconazole	Miconazole, CAS-RN: 22916-47-8, DTXSID6023319	None
486	minocycline	Minocycline, CAS-RN: 10118-90-8, DTXSID1045033	277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
676	Mitochondrial ETC inhibitors		None
684	Molinate	Molinate, CAS-RN: 2212-67-1, DTXSID6024206	None
64	Mono(2-ethylhexyl) phthalate		457: Succinate dehydrogenase inhibition leading to increased insulin resistance through reduction in circulating thyroxine
569	monobenzyl phthalate		None
692	Montelukast	Montelukast, CAS-RN: 158966-92-8, DTXSID9023334	None
222	MPP+		3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
403	MS-275	MS-275, CAS-RN: 209783-80-2, DTXSID0041068	274: Histone deacetylase inhibition leads to impeded craniofacial development
306	Multi-walled carbon nanotubes		409: Frustrated phagocytosis leads to malignant mesothelioma
669	Mycotoxin	Mycotoxin, CAS-RN: NOCAS, DTXSID0040884	None
572	N-(5-Hydroxytricyclo[3.3.1.13,7]dec-2-yl)-α,α-dimethyl-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazineacetamide		348: Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory
780	N-Acetylsphingosine	N-Acetylsphingosine, CAS-RN: 3102-57-6, DTXSID201016802	534: Activation of Protein kinase C leads to Kidney Failure
80	N-methyl Carbamates		405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function
268	n/a		None
589	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide		None
588	Nʹ-((4-Oxo-4H-chromen-3-yl)methylene)nicotinohydrazide Pimozide		None
315	Nabam-sodium	Nabam-sodium, CAS-RN: 142-59-6, DTXSID5020603	242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity
206	Nafenopin	Nafenopin, CAS-RN: 3771-19-5, DTXSID8020911	37: PPARα activation leading to hepatocellular adenomas and carcinomas in rodents
634	nanomaterials		2 AOPs 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
224	nanoparticles		3 AOPs 144: Endocytic lysosomal uptake leading to liver fibrosis 392: Decreased fibrinolysis and activated bradykinin system leading to hyperinflammation 451: Interaction with lung resident cell membrane components leads to lung cancer
733	Nanoparticles and micrometer		None